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that's, stimulation of CD74 with exogenous MIF could result in an too much inflammatory point out, as MIF is effective at stimulating CXCR2 and CXCR4 receptors in addition to CD74. CXCR2 and CXCR4 receptors when activated encourage influx of neutrophils and lymphocytes, respectively (63, sixty four). I didn’t obtain any positives about This syst